IT & Software

ADME/DMPK Technical Expert

Syngenta

Bracknell · Berkshire · United Kingdom

Overview

In this role you will advance ADME, PK/TK understanding to support the development and registration of sustainable crop protection products. You will operate within the Analytical Metabolism and Methods group, collaborating with study managers and external CROs to design studies, interpret data, and ensure timely data delivery. You will translate complex DMPK/ADME data into actionable insights for project teams and contribute to regulatory-compliant study design. This position offers a meaningful opportunity to shape product safety strategies in a global, cross-functional environment.

Pay / Benefits
  • generous pension scheme
  • bonus scheme
  • private medical & life insurance
  • up to 31.5 days annual holiday
  • large campus environment
  • training and development opportunities
Responsibilities
  • Overseeing CRO delivery and ensuring timely data generation and review of study documents
  • Delivering technical insights from ADME and PK/TK data to metabolism teams
  • Applying regulatory expertise and keeping abreast of global guidance (GLP, OECD) implications
  • Partnering with CROs and external suppliers to transfer knowledge and resolve technical challenges
  • Driving continuous improvement through new processes, guidance documents, and report templates
  • Serving as a scientific contributor within the ADME, PK/TK expert area across relevant functions
Key requirements
  • Degree or equivalent in biology- or chemistry-related discipline
  • Significant knowledge in DMPK/ADME with PK/TK expertise
  • Familiarity with global Regulatory Test Guidelines (e.g., OECD 417) and GLP for crop protection chemical registrations
  • Experience translating complex datasets into safety/regulatory insights
  • Practical knowledge of quantitative PK/TK principles including non-compartmental analysis (NCA)
  • Ability to collaborate within diverse scientific teams and with external stakeholders
  • Strong organization, prioritization, and deliverables tracking across multiple projects
  • Excellent oral and written communication for technical reports and presentations
  • Willingness to learn and apply new skills promptly
  • Desirable: in vitro/in vivo xenobiotic mammalian metabolism knowledge and cross-species comparisons
  • Desirable: experience managing services via third-party organisations
  • collaboration
  • attention to detail
  • analytical thinking
  • DMPK/ADME
  • pharmacokinetics (PK)
  • toxicokinetics (TK)

Reference: WJ-747_31049651

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