IT & Software

Principal Statistical Programmer

GSK

County Durham · County Durham · United Kingdom

Overview

As Principal Statistical Programmer, you lead programming across studies, driving high-quality analysis outputs and technical excellence. You’ll mentor junior programmers, adopt modern tools and AI-enabled workflows, and ensure regulatory compliance. You contribute to strategy, stand up robust governance for clinical data, and partner with cross-functional teams to accelerate HIV programs. This role offers impact through shaping analytics for Phase 1–4 studies and advancing data-driven decision making.

Pay / Benefits
  • comprehensive benefits program
  • equal opportunity employer
  • inclusive culture
  • opportunity for career progression
  • global mission in HIV care
Responsibilities
  • Lead programming for studies ensuring efficient development and validation of analysis packages
  • Select appropriate tools/languages and solve complex technical challenges
  • Identify and implement improvements including AI/ML
  • Contribute to departmental initiatives and technical strategy
  • Ensure adherence to standards (GPP, CDISC) and regulatory requirements; perform QC on outputs and documents
  • Maintain governance and oversee TMF compliance
  • Drive adoption of modern technologies, standards, and Agile practices
  • Provide technical input on programming strategies and study design; act as SME for emerging tools
  • Communicate technical concepts, risks, and timelines to stakeholders; mentor junior programmers
  • Support sprint planning and project delivery; collaborate cross-functionally; manage data access; support regulatory interactions and CoE activities
  • Lead Programmer for complex or multiple studies; ensure quality, compliance, and efficient execution; make data-driven decisions and address risks/issues
Key requirements
  • Bachelor’s degree in Statistics, Computer Science, or a related field
  • Expertise in R programming
  • 6+ years of clinical programming experience
  • 5+ years of experience in the Pharmaceutical or Biotechnology industry
  • Experience using generative AI tools and coding assistants (e.g., GitHub Copilot, Codex, and Claude) to improve programming efficiency and workflows
  • Excellent analytical and problem-solving abilities
  • Strong communication and stakeholder management
  • Mentorship and leadership of junior team members
  • R programming
  • Generative AI tools and coding assistants (GitHub Copilot, Claude, Codex)
  • Git-based workflows and automation pipelines

Reference: WJ-747_30153654

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